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DETROIT -- Wide receiver Mohamed Massaquoi was a player many within the Cleveland Browns organization had high hopes for entering the 2012 season.

After a year of nagging injuries in 2011, Massaquoi reported to camp healthy, ready to compete for playing time and willing to show everyone how improved he was from a season ago. Those plans changed quickly in Friday night’s 19-17 come-from-behind preseason win over the Detroit Lions at Ford Field.

Massaquoi caught a 12-yard pass from quarterback Brandon Weeden on the team’s first offensive play of the preseason and turned to gain extra yardage. While trying to turn the ball upfield, Massaquoi was hit by two Lions. Following the play, the fourth-year Brown was slow to get to his feet and Detroit players signaled to the Browns sideline for assistance.

Able to walk off the field under his own power, Massaquoi was accompanied to the sideline by a member of the team’s medical staff and did not return to the game.

“The first play of the game, it’s a concussion,” Browns coach Pat Shurmur said in his postgame press conference. “We are following league protocols. He came off and we put him through the paces. We’re following protocol and we’ll just have to see. We followed league protocols. He came off with the symptoms, so we followed the protocol.”

Massaquoi has dealt with concussions previously in his NFL career.

His most infamous came at the hands of Pittsburgh Steelers linebacker James Harrison two seasons ago. While going over the middle of the field to try and catch a pass from quarterback Colt McCoy, Massaquoi was hit high by Harrison and did not return to that game.

“I’m always concerned about injuries and I think he’s going to deal with this,” Shurmur said. “We’re going to go through the process and when he’s healthy enough to play, then, we’ll put him back out there and not before then.

“Just like any other injury that happens, you circle the wagons; you put in the next guy and you go. I think that’s part of the greatness of this game. When a spot is made, someone takes over and they go in and play. You might see something that you didn’t expect from the other guys.”

Massaquoi was one of four Browns to suffer injuries in the first half of Friday’s win over the Lions.

Defensive lineman Scott Paxson was helped to the sideline with a knee injury and defensive back Dimitri Patterson left the game with an ankle injury after colliding with teammate Ray Ventrone while trying to seal off an edge in run defense.

Tight end Jordan Cameron caught a 42-yard pass from McCoy, the team’s longest offensive play of the game, but landed with former Browns safety Sean Jones coming down on top of him. Cameron suffered an injured back and did not return to the game.

“It’s like catches for receivers; sometimes, they come in bunches and we had a couple guys go down,” Shurmur said. “At the end of it, after they’ve been evaluated a little bit, I’m just hoping some of these are minor and we’ll move on. If you give some of those other guys that we talk about all summer, more reps and we get to see more from the young guys, (it) is as important in the preseason as going out and winning the games.”