Cleveland Browns
| Position | Name | Injury | 12/30/2015 | 12/31/2015 | 1/1/2016 | Status |
| WR | T. Benjamin | Ankle | DNP | Limited | Limited | Questionable |
| DE | D. Bryant | Thumb | Full | Full | Full | Probable |
| LB | K. Dansby | Toe | DNP | DNP | DNP | Questionable |
| QB | J. Manziel | Concussion | DNP | DNP | DNP | OUT |
| WR | M. Moore | Concussion | DNP | DNP | DNP | OUT |
| RB | R. Mostert | Ankle | DNP | Limited | Limited | Questionable |
| DE | R. Starks | Not Injury Related | DNP | Full | Full | |
| T | J. Thomas | Knee | DNP | DNP | Limited | Questionable Questionable |
| DB | K. Williams | Shoulder | Limited | Limited | Limited | Questionable |
| DB | T. Williams | Concussion | DNP | DNP | DNP | OUT |
| RB | G. Winston | Concussion | DNP | DNP | DNP | OUT |
Pittsburgh Steelers
| Position | Name | Injury | 12/30/2015 | 12/31/2015 | 1/1/2016 | Status |
| DB | W. Allen | Not Injury Related | DNP | Full | Probable | |
| CB | A. Blake | Back | DNP | DNP | Full | Probable |
| S | M. Mitchell | Shoulder | DNP | Full | Full | Questionable |
| QB | B. Roethlisberger | Illness | DNP | Full | Full | Probable |
| LB | J. Harrison | Illness | DNP | DNP | Full | Questionable |
| WR | M. Bryant | Illness | DNP | DNP | Full | Probable |
| DB | W. Gay | Not Injury Related | DNP | Full | Full | Probable |
| TE | H. Miller | Not Injury Related | DNP | Full | Full | Probable |
| CB | D. Grant | Groin | Limited | DNP | Full | Questionable |
| LB | R. Shazier | Not Injury Related | DNP | Full | Probable | |
| TE | M. Spaeth | Not Injury Related | DNP | Full | Probable |
Full Participation (FP)=100% of player's normal reps; Limited (LP)=less than 100% of player's normal reps; Did Not Participate in Practice (DNP); Bold indicates change in status; Probable=virtual certainty player will be available for normal duties. Questionable=50/50% chance player will not play; Doubtful=at least 75% chance player will not play; Out = will not play.
