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Cleveland Browns
| Position | Name | Injury | 9/20/2017 | 9/21/2017 | 9/22/2017 | Status |
| WR | Kenny Britt | Knee | FULL | FULL | FULL | |
| WR | Sammie Coates | Hamstring | DNP | DNP | DNP | DOUBTFUL |
| LB | Jamie Collins Sr. | Concussion | DNP | DNP | DNP | OUT |
| DL | Myles Garrett | Ankle | DNP | DNP | DNP | DOUBTFUL |
| DL | T.Y. McGill | Back | LIMITED | LIMITED | LIMITED | QUESTIONABLE |
| TE | Randall Telfer | Knee | FULL | FULL | ||
| OL | Joe Thomas | Knee | DNP | FULL | ||
| OL | Kevin Zeitler | Thumb | FULL | FULL |
Indianapolis Colts
| Position | Name | Injury | 9/20/2017 | 9/21/2017 | 9/22/2017 | Status |
| WR | Kamar Aiken | Hip | LIMITED | LIMITED | LIMITED | QUESTIONABLE |
| LB | Tarell Basham | Heat exhaustion | LIMITED | FULL | FULL | |
| DB | Darius Butler | Hamstring | LIMITED | LIMITED | LIMITED | QUESTIONABLE |
| DB | Vontae Davis | Groin | LIMITED | LIMITED | LIMITED | DOUBTFUL |
| RB | Frank Gore | Not injury related | DNP | FULL | ||
| OL | Ryan Kelly | Foot | DNP | DNP | DNP | OUT |
| QB | Andrew Luck | Shoulder | DNP | DNP | DNP | OUT |
| RB | Marlon Mack | Shoulder | LIMITED | DNP | DNP | OUT |
| OL | Jack Mewhort | Not injury related | DNP | FULL | ||
| DB | Chris Milton | Hamstring | LIMITED | LIMITED | LIMITED | QUESTIONABLE |
| LB | Antonio Morrison | Elbow | FULL | FULL | FULL | |
| WR | Chester Rogers | Hamstring | DNP | DNP | DNP | OUT |
| LB | Anthony Walker | Hamstring | DNP | DNP | DNP | OUT |
| TE | Brandon Williams | Calf | DNP | FULL | FULL | QUESTIONABLE |
| DB | Quincy Wilson | Knee | DNP | DNP | DNP | OUT |
Full Participation (Full)=100% of player's normal reps; Limited =less than 100% of player's normal reps; Did Not Participate in Practice (DNP). OUT = Will not play; DOUBTFUL = Unlikely to Play; QUESTIONABLE = Uncertain if player will play.
