Making his NFL debut, DL Myles Garrett recorded two sacks, including one on his first NFL play. Garrett is the only No. 1 overall pick to record multiple sacks in his NFL debut and the first to register at least one sack since Indianapolis DL Steve Emtman in 1992. Garrett is the first Browns player to record multiple sacks in his NFL debut since DL Charles Buchanan had 2.5 in 1988.
Rookie TE David Njoku recorded three receptions for 48 yards, including a 21-yard touchdown. His three receiving scores this season lead the team and are tied for the most by a Browns rookie tight end.
Most receiving TDs by a Browns rookie tight end
| Player | Year | Games | Total |
| 1. David Njoku | 2017 | 5 | 3 |
| Derek Tennell | 1987 | 11 | 3 |
| Harry Holt | 1983 | 15 | 3 |
| Oscar Roan | 1975 | 14 | 3 |
| Milt Morin | 1966 | 11 | 3 |
RB Duke Johnson Jr. recorded three receptions for 63 yards, including a 41-yard touchdown. He added 20 rushing yards. Johnson has scored a touchdown in three consecutive games (two rushing and one receiving).
DB Jason McCourty recorded an interception, one forced fumble and two passes defensed. Through five games this season, he has two interceptions and two forced fumbles.
QB Kevin Hogan, who played the second half, completed 16 of 19 passes for 194 yards with two touchdowns, one interception and a 122.4 rating. To open the second half, Hogan completed all five of his passing attempts for 52 yards on a 10-play, 75-yard touchdown drive.
The Browns rushed for a season-high 140 yards. RB Isaiah Crowell (60), Hogan (30), rookie QB DeShone Kizer (29) and Johnson (20) all rushed for at least 20 yards.
LB James Burgess Jr. led the team with six tackles and one sack. He is tied for the team lead with two sacks this season.
LT Joe Thomas extended his consecutive snaps streak to 10,262, the longest active streak in the league and believed to be the longest streak in NFL history. The 10-time Pro Bowler has started all 165 career games and hasn't missed an offensive play since being selected by the Browns with the third overall pick in the 2007 draft.
RB Isaiah Crowell rushed for a season high 60 yards. With 2,459 career rushing yards, he ranks ninth on the Browns all-time rushing list.
Browns all-time rushing yardage leaders
| Player | Years | Games | Att. | Yards | TD |
| 6. Earnest Byner | 1984-95 (7) | 99 | 862 | 3,364 | 27 |
| 7. Ernie Green | 1962-68 (7) | 89 | 668 | 3,204 | 15 |
| 8. Jamal Lewis | 2007-09 (3) | 40 | 720 | 2,806 | 13 |
| 9. Isaiah Crowell | 2014-17 (4) | 53 | 593 | 2,459 | 19 |
| 10. Bobby Mitchell | 1958-61 (4) | 50 | 423 | 2,297 | 16 |
WR Ricardo Louis set a career-high with 71 receiving yards and tied a career mark with five receptions.
WR Kasen Williams set career highs in receptions (four) and receiving yards (33).
LB James Burgess Jr. left the game with a knee injury and did not return.
