Isaiah McGuire
DE
#57
Experience: 4 years
Height: 6-4
Weight: 268 lbs
College: Missouri
2025 SEASON
- Solo13
- SCK2
- FF1
- INT--
Preseason
| WK | Game Date | OPP | RESULT | Total | Solo | AST | SCK | SFTY | PDEF | INT | YDS | AVG | LNG | TDS | FF | FR |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 3 | 08/23/2025 | Rams | W 19 - 17 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | ||||||
| 2 | 08/16/2025 | @Eagles | W 22 - 13 | 2 | 1 | 1 | 1 | 0 | 0 | 0 | ||||||
| 1 | 08/08/2025 | @Panthers | W 30 - 10 |
Regular Season
| WK | Game Date | OPP | RESULT | Total | Solo | AST | SCK | SFTY | PDEF | INT | YDS | AVG | LNG | TDS | FF | FR |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 18 | 01/04/2026 | @Bengals | W 20 - 18 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||||
| 17 | 12/28/2025 | Steelers | W 13 - 6 | |||||||||||||
| 16 | 12/21/2025 | Bills | L 20 - 23 | |||||||||||||
| 15 | 12/14/2025 | @Bears | L 3 - 31 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | ||||||
| 14 | 12/07/2025 | Titans | L 29 - 31 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||||
| 13 | 11/30/2025 | 49ers | L 8 - 26 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | ||||||
| 12 | 11/23/2025 | @Raiders | W 24 - 10 | 7 | 3 | 3 | 1 | 0 | 0 | 0 | ||||||
| 11 | 11/16/2025 | Ravens | L 16 - 23 | 3 | 1 | 2 | 0 | 0 | 0 | 0 | ||||||
| 10 | 11/09/2025 | @Jets | L 20 - 27 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | ||||||
| 8 | 10/26/2025 | @Patriots | L 13 - 32 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | ||||||
| 7 | 10/19/2025 | Dolphins | W 31 - 6 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | ||||||
| 6 | 10/12/2025 | @Steelers | L 9 - 23 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | ||||||
| 5 | 10/05/2025 | Vikings | L 17 - 21 | 2 | 0 | 0 | 0 | 0 | 0 | 1 | ||||||
| 4 | 09/28/2025 | @Lions | L 10 - 34 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | ||||||
| 3 | 09/21/2025 | Packers | W 13 - 10 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | ||||||
| 2 | 09/14/2025 | @Ravens | L 17 - 41 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | ||||||
| 1 | 09/07/2025 | Bengals | L 16 - 17 | 6 | 4 | 2 | 1 | 0 | 0 | 0 |
Biography
Career Transactions
Originally selected by the Cleveland Browns in the fourth round (126th overall) of the 2023 NFL Draft.
Key Notes
- Appeared in 16 games with three starts for the Browns in 2024, recording 34 tackles, three forced fumbles and 2.5 sacks, including a strip-sack of Joe Burrow at Cincinnati on Dec. 22, 2024.
- Recorded first career sack at Cincinnati on Jan. 7, 2024.
- Played 40 games (30 starts) at Missouri over four years (2019-22) and totaled 103 tackles, 16.5 sacks and one forced fumble. His 16.5 sacks were 13th in program history.
- Started in all 12 games as a senior and recorded 7.5 sacks.