Isaiah McGuire

DE

#57

Experience: 4 years

Height: 6-4

Weight: 268 lbs

College: Missouri

2025 SEASON

Solo
13
SCK
2
FF
1
INT
--

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Recent Games

WK	OPP	RESULT	TKL	AST	COMBINED	SOLO	SCK	SFTY	PDEF	FF
1	Bengals	L 16 - 17	4	2	6	4	1	0	0	0
2	@Ravens	L 17 - 41	0	1	1	0	0	0	0	0
3	Packers	W 13 - 10	0	1	1	0	0	0	0	0
4	@Lions	L 10 - 34	0	1	1	0	0	0	0	0
5	Vikings	L 17 - 21	2	0	2	0	0	0	0	1
6	@Steelers	L 9 - 23	1	0	1	1	0	0	0	0
7	Dolphins	W 31 - 6	1	1	2	0	0	0	0	0
8	@Patriots	L 13 - 32	2	0	2	2	0	0	0	0
10	@Jets	L 20 - 27	2	0	2	2	0	0	0	0
11	Ravens	L 16 - 23	1	2	3	1	0	0	0	0
12	@Raiders	W 24 - 10	4	3	7	3	1	0	0	0
13	49ers	L 8 - 26	0	1	1	0	0	0	0	0
14	Titans	L 29 - 31	0	0	0	0	0	0	0	0
15	@Bears	L 3 - 31	0	1	1	0	0	0	0	0
16	Bills	L 20 - 23
17	Steelers	W 13 - 6
18	@Bengals	W 20 - 18	0	0	0	0	0	0	0	0

Career Stats

Defense Career

SEASON	TEAM	G	GS	TKL	AST	COMBINED	SOLO	SCK	INT	YDS	AVG	LNG	TDS	FF	OPP FR
2023	Cleveland Browns	4	1	5	1	6	4	1						0
2024	Cleveland Browns	16	3	18	18	36	14	2.5						3
2025	Cleveland Browns	17	8	17	13	30	13	2						1
TOTAL		37	12	40	32	72	31	5.5	0	0	0	0	0	4	0

Biography

Career Transactions

Originally selected by the Cleveland Browns in the fourth round (126th overall) of the 2023 NFL Draft.

Key Notes

Appeared in 16 games with three starts for the Browns in 2024, recording 34 tackles, three forced fumbles and 2.5 sacks, including a strip-sack of Joe Burrow at Cincinnati on Dec. 22, 2024.

Recorded first career sack at Cincinnati on Jan. 7, 2024.

Played 40 games (30 starts) at Missouri over four years (2019-22) and totaled 103 tackles, 16.5 sacks and one forced fumble. His 16.5 sacks were 13th in program history.

Started in all 12 games as a senior and recorded 7.5 sacks.

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"Three Plays, Three Sacks!" Call of the Game - Week 1 vs. Bengals

Go inside the booth with Andrew Siciliano and Nathan Zegura to hear the Call of the Game from Week 1 vs. Cincinnati, presented by Microsoft Copilot + PC.

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Isaiah McGuire's 9-yard sack forces Eagles into a punt

Cleveland Browns' defensive end Isaiah McGuire grabs Philadelphia Eagles' quarterback Dorian-Thompson Robinson around the legs for a 9-yard sack.

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BPA Season Finale with new OL Coach Mike Bloomgren and DE Isaiah McGuire – Best Podcast Available

On this week's final off-season episode of the Best Podcast Available new OL Coach Mike Bloomgren discusses the challenges his room faces this season and how the guys performed in minicamp. DE Isaiah McGuire joins the show as well to discuss his goals for 2025 and Browns Play by Play Voice Andrew Siciliano and Jason Gibbs recap the off-season and look ahead to training camp 2025!

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Cleveland Browns Daily - Updated Roster Deep Dive

On a "First Friday" episode of Browns Daily the guys give you a post-draft updated roster breakdown of the Browns offense and defense. Plus hear from new Browns DE Isaiah McGuire.

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Cleveland Browns Draft Recap: Isaiah McGuire, Dorian Thompson-Robinson, & More! | 2 Minute Drill

Nathan Zegura breaks down the final 4 draft picks the Browns acquired during the 2023 NFL Draft.

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We picked some DAWGS in Kansas City | 2023 NFL Draft | Cleveland Browns

The Browns added 7 players in the 2023 NFL Draft!

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DE Isaiah McGuire gets The Draft Call at No. 126 Overall

DE Isaiah McGuire hears from General Manager Andrew Berry and Head Coach Kevin Stefanski as the Browns select him with the 126th pick in the 2023 NFL Draft.

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Video: Browns select Isaiah McGuire with No. 126 pick in 2023 draft

The Cleveland Browns select Missouri Tigers EDGE rusher Isaiah McGuire in Round 4 of the 2023 NFL Draft with the No. 126 overall pick (via a trade with the Minnesota Vikings).